Bioprinting - Additive production of artificial tissue

© Fraunhofer IGB

The Fraunhofer IGB provides formulation of biomaterials based on hydrogels of the natural tissue matrix for bioprinting applications.

We develop sophisticated compositions of hydrogels which mimic the matrix of specific tissues and can be applied in printing processes.

We use for example cross-linkable gelatin, hyaluronic acid, and chondroitin sulphate, inorganic fillers like hydroxy apatite, and collagen to generate tailored 3D environments for tissue specific cells such as chondrocytes, adipocytes, endothelial cells,  as well as for support of differentiation of mesenchymal stem cells.

We adapt the viscoelastic properties of matrices to liquid handling and characterize the biological effects on cells.

We support your developments of artifical tissue systems, please contact us.

 

Project:

DynaImplant (FhG), Artivasc-EU

Publication:

A. Wenz et al. Hydroxyapatite-modified gelatin bioinks for bone bioprinting. BioNanoMaterials. 17: 179, 2016.

B. Huber et al., Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering. J Biomater Appl;30(6):699-710., 2016.
S. Stier et al. Development of ECM-mimicking hydrogel bioinks and fabrication of zonal cartilage equivalents by dispensing technology, 2017 -  Manuscript in Preparation

Links: 

http://www.artivasc.eu/

Pending:

EP2621713 B1

Contact:

Dr. Achim Weber, 0711 970-4022,  achim.weber@igb.fraunhofer.de